Luciferase Reporter Gene Assay on Human 5-HT Receptor: Which Response Element Should Be Chosen?
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چکیده
منابع مشابه
Luciferase Reporter Gene Assay on Human 5-HT Receptor: Which Response Element Should Be Chosen?
Serotonin (5-HT) receptors are valuable molecular targets for antipsychotic drug discovery. Current reported methods for detecting 5-HT receptors, such as cAMP accumulation and calcium influx assay, are often demanding specialized instruments and inconvenient. The luciferase reporter gene assay, based on the responsible-element-regulated expression of luciferase, has been widely applied in the ...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2015
ISSN: 2045-2322
DOI: 10.1038/srep08060